Pharmaceutical grade HPMC Hydroxypropyl Methylcellulose
Pharma grade HPMC products are derived from natural refined cotton linter and wood pulp, meeting all the requirements of the USP, EP, JP, along with Kosher and Halal Certifications.Pharmaceutical grade HPMC is in compliance with FDA, EU and FAO/WHO guidelines, and is manufactured in accordance with GMP standard, retaining ISO9001 and ISO14001 certifications as well.
Pharma HPMC comes in diverse viscosity ranges from 3 to 200,000 cps, and it can be widely used for tablet coating, granulation, binder, thickener, stabilizer and making vegetable HPMC capsule.
1.Chemical Specification
| Specification |
60AX ( 2910 ) |
65AX ( 2906 ) |
75AX ( 2208 ) |
|
Gel temperature (℃) |
58-64 |
62-68 |
70-90 |
|
Methoxy (WT%) |
28.0-30.0 |
27.0-30.0 |
19.0-24.0 |
|
Hydroxypropoxy (WT%) |
7.0-12.0 |
4.0-7.5 |
4.0-12.0 |
|
Viscosity(cps, 2% Solution) |
3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000 |
||
2.Product Grade:
|
Grade Name |
Viscosity(cps) |
Remark |
|
HPMC 60AX5 (E5) |
4.0-6.0 |
2910 |
|
HPMC 60AX6 (E6) |
4.8-7.2 |
|
|
HPMC 60AX15 (E15) |
12.0-18.0 |
|
|
HPMC 60AX4000 (E4M) |
3200-4800 |
|
|
HPMC 65AX50 (F50) |
40-60 |
2906 |
|
HPMC 75AX100 (K100) |
80-120 |
2208 |
|
HPMC 75AX4000 (K4M) |
3200-4800 |
|
|
HPMC 75AX100000 (K100M) |
80000-120000 |
3.Application
Pharma Grade HPMC enable the production of controlled-release formulations with the convenience of the most widely used tablet-binding mechanism. Pharma Grade offer good powder flow, content uniformity, and compressibility, making them well suited for direct compression.
|
Pharma Excipients Application |
Pharma Grade HPMC |
Dosage |
|
Bulk Laxative |
75AX4000,75AX100000 |
3-30% |
|
Creams, Gels |
60AX4000,75AX4000 |
1-5% |
|
Ophthalmic Preparation |
60AX4000 |
01.-0.5% |
|
Eye Drops Preparations |
60AX4000 |
0.1-0.5% |
|
Suspending Agent |
60AX4000, 75AX4000 |
1-2% |
|
Antacids |
60AX4000, 75AX4000 |
1-2% |
|
Tablets Binder |
60AX5, 60AX15 |
0.5-5% |
|
Convention Wet Granulation |
60AX5, 60AX15 |
2-6% |
|
Tablet Coatings |
60AX5, 60AX15 |
0.5-5% |
|
Controlled Release Matrix |
75AX100000,75AX15000 |
20-55% |
4. Features and Benefits:
- Improves product flow characteristics
- Reduces processing times
- Identical, stable dissolution profiles
- Improves content uniformity
- Reduces production costs
- Retains tensile strength after double compaction (roller compaction) process
5.Packaging
The standard packing is 25kg/drum
20’FCL: 9 ton with palletized; 10 ton unpalletized.
40’FCL: 18 ton with palletized; 20 ton unpalletized.
Cangzhou Bohai New District Chemistry Co., Ltd. is a professional Hydroxypropyl Methylcellulose (HPMC) Pharmaceutical Grade cellulose ether manufacturer in China, located in the Lingang Economic and Technological Development Zone Chemical Park,Cangzhou Bohai New District, a national level chemical park, close to Beijing,Tianjin and Shandong .80KM distance to Tianjin seaport.
The production capacity is 27000 tons/year. The products are: Hydroxypropyl Methyl Cellulose (HPMC), Hydroxyethyl Methyl Cellulose (HEMC), Methyl Cellulose (MC), Hydroxyethyl Cellulose (HEC), Ethyl Cellulose (EC) etc.